| Assay ID | Title | Year | Journal | Article |
|---|
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID603872 | Displacement of [125I]BE-2254 from human adrenergic Alpha-1B receptor expressed in HEK293 cells | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7
| Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes. |
| AID277057 | Displacement of [125I]BE2254 from human cloned adrenergic alpha 1B receptor expressed in HEK293 cells | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24
| New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: high affinity ligands for the alpha(1)-adrenoceptor subtypes. |
| AID239341 | Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from rat hippocampus | 2005 | Journal of medicinal chemistry, Apr-07, Volume: 48, Issue:7
| Synthesis of 3-arylpiperazinylalkylpyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as novel, potent, and selective alpha1-adrenoceptor ligands. |
| AID603868 | Binding affinity to adrenergic alpha1A receptor | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7
| Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes. |
| AID277060 | Antagonist activity at adrenergic alpha 1B receptor in rat spleen | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24
| New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: high affinity ligands for the alpha(1)-adrenoceptor subtypes. |
| AID36194 | Binding affinity towards Alpha-2 adrenergic receptor in human platelet membranes using [3H]yohimbine | 1991 | Journal of medicinal chemistry, Jun, Volume: 34, Issue:6
| Pyrimido[5,4-b]indole derivatives. 1. A new class of potent and selective alpha 1 adrenoceptor ligands. |
| AID277058 | Displacement of [125I]BE2254 from human cloned adrenergic alpha 1D receptor expressed in HEK293 cells | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24
| New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: high affinity ligands for the alpha(1)-adrenoceptor subtypes. |
| AID603873 | Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7
| Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes. |
| AID37174 | Alpha-1-adrenergic receptor binding affinity of the compound, value taken from literature | 2001 | Journal of medicinal chemistry, Jun-21, Volume: 44, Issue:13
| Synthesis, biological evaluation, and pharmacophore generation of new pyridazinone derivatives with affinity toward alpha(1)- and alpha(2)-adrenoceptors. |
| AID277059 | Antagonist activity at adrenergic alpha 1A receptor in rat prostatic vas deferens | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24
| New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: high affinity ligands for the alpha(1)-adrenoceptor subtypes. |
| AID277061 | Antagonist activity at adrenergic alpha 1D receptor in rat thoracic aorta | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24
| New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: high affinity ligands for the alpha(1)-adrenoceptor subtypes. |
| AID603869 | Binding affinity to adrenergic Alpha-1B receptor | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7
| Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes. |
| AID603870 | Binding affinity to adrenergic Alpha-1D receptor | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7
| Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes. |
| AID243032 | Relative binding affinity for 5-hydroxytryptamine 1A and Alpha-1 adrenergic receptors | 2005 | Journal of medicinal chemistry, Apr-07, Volume: 48, Issue:7
| Synthesis of 3-arylpiperazinylalkylpyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as novel, potent, and selective alpha1-adrenoceptor ligands. |
| AID37476 | In vitro binding affinity at human Alpha-1B adrenergic receptor. | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| New pyrimido[5,4-b]indoles as ligands for alpha(1)-adrenoceptor subtypes. |
| AID603871 | Displacement of [125I]BE-2254 from human adrenergic alpha1A receptor expressed in HEK293 cells | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7
| Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes. |
| AID36147 | Binding affinity for Alpha-1 adrenergic receptor measured by displacing [3H]prazosin from rat cortical membranes | 1991 | Journal of medicinal chemistry, Jun, Volume: 34, Issue:6
| Pyrimido[5,4-b]indole derivatives. 1. A new class of potent and selective alpha 1 adrenoceptor ligands. |
| AID171949 | Inhibition of [3H]inositol Phosphate formation by 100 uM norepinephrine in rat hippocampal slices. | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| New pyrimido[5,4-b]indoles as ligands for alpha(1)-adrenoceptor subtypes. |
| AID239153 | Inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor from rat cortex | 2005 | Journal of medicinal chemistry, Apr-07, Volume: 48, Issue:7
| Synthesis of 3-arylpiperazinylalkylpyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as novel, potent, and selective alpha1-adrenoceptor ligands. |
| AID36751 | Binding affinity towards Alpha-1A adrenergic receptor | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| New pyrimido[5,4-b]indoles as ligands for alpha(1)-adrenoceptor subtypes. |
| AID41330 | Binding affinity towards Beta-2 adrenergic receptor in human peripheral mononuclear leukocyte membranes using [125I]pindolol | 1991 | Journal of medicinal chemistry, Jun, Volume: 34, Issue:6
| Pyrimido[5,4-b]indole derivatives. 1. A new class of potent and selective alpha 1 adrenoceptor ligands. |
| AID277056 | Displacement of [125I]BE2254 from human cloned adrenergic alpha 1A receptor expressed in HEK293 cells | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24
| New pyrimido[5,4-b]indoles and [1]benzothieno[3,2-d]pyrimidines: high affinity ligands for the alpha(1)-adrenoceptor subtypes. |
| AID613984 | Displacement of [3H]-8-OH-DPAT from 5HT1A in CRL:CD(SD)BR-COBS rat brain hippocampus after 30 mins by liquid scintillation spectrometry | 2011 | Bioorganic & medicinal chemistry, Sep-01, Volume: 19, Issue:17
| Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for the α1-adrenoceptors. |
| AID4032 | Binding affinity for 5-hydroxytryptamine 1A receptor measured by displacing [3H]8-OH-DPAT from rat cortical membranes | 1991 | Journal of medicinal chemistry, Jun, Volume: 34, Issue:6
| Pyrimido[5,4-b]indole derivatives. 1. A new class of potent and selective alpha 1 adrenoceptor ligands. |
| AID35466 | Binding affinity towards Alpha-1D adrenergic receptor | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| New pyrimido[5,4-b]indoles as ligands for alpha(1)-adrenoceptor subtypes. |
| AID613983 | Displacement of [3H]prazosin from alpha1-ARs in CRL:CD(SD)BR-COBS rat brain cortex after 30 mins by liquid scintillation spectrometry | 2011 | Bioorganic & medicinal chemistry, Sep-01, Volume: 19, Issue:17
| Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for the α1-adrenoceptors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |